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Biophysical Immunology Lab

Biophysical immunology envisions to understand the interplay of biophysics and immunology in health and disease.

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Image Credit: Shuyang Xu, Huw Colin-York

blue and white water splash
Get In Touch

Biophysical Immunology Lab

Biophysical immunology envisions to understand the interplay of biophysics and immunology in health and disease.

Explore Our Research

Image Credit: Shuyang Xu, Huw Colin-York

Our Thinking

Physics of Human Immunity in Health and Disease

The Biophysical Immunology (BPI) laboratory aims to understand the biological significance of mechanobiology on the human immune system in health and disease. For this goal we develop advanced technology, microscopy, and analysis approaches.

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Image Credit: Shuyang Xu, Huw Colin-York

10 Year Anniversary of the Biophysical Immunology Laboratory

Research Highlights

Mechanical force matters in early T cell activation

Nature Methods 2026

Mechanobiology 2026

The Mechanobiologist’s dilemma: Force, stiffness, and the illusion of adaptation
Metabolic profiling of steatotic liver disease by fluorescence lifetime imaging microscopy

Nature Communications Medicine 2026

Trends Open 2026

T cells are blind to the dark mechanics of tumors

PNAS 2024

More Is More: Why Cell Number Matters Profoundly In Microscopy
Astigmatic Traction force microscopy (aTFM)

Nature Communications 2021

Lab Directory

The BPI Ecosystem

Access our published research, proprietary technology, and academic opportunities.

Who We Are

Our Thinking

What We Publish

People

Research

Publications

Explore our team that employs expertise from physics, cell-biology, and immunology. Learn about our people, research, and commitment to science.

Biophysical immunology envisions to understand the interplay of biophysics and immunology in health and disease.

Learn about our most recent public articles, reviews, and journal articles.

What We Make

With Whom We Work

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Where We Are

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Contact

Learn about our new immunology, mechanics, microscopy, and analysis informatics technologies.

Find information about our scientific collaborators in Europe, Asia, and America.

Join our team and help us to resolve contentious biomedical research questions.

The BPI lab is located at the Kennedy Institute of Rheumatology (KIR) at the University of Oxford and the Rosalind Franklin Institute (RFI) in the UK.

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Collaborate with the BPI Lab.

We partner with leading immunologists and physical scientists globally to solve complex biophysical questions.